GWAS
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    • 2. REGENIE
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GWAS tools: BOLT-LMM & REGENIE

Lieven Clement

Link between PCA-regression, ridge regression and linear mixed models


This site contains background information on

  • Linear Models and Projections
  • Linear Mixed Models (LMM)
  • Ridge regression
  • PCA regression

needed to understand the BOLT-LMM and REGENIE method used in GWAS applications.

Materials prepared for the journal clubs (09/04/2024 & 11/04/2024) of the Vaudel and Johansson groups

Background GWAS (INSIST seminar 29/05/2024)

  • Background GWAS

BOLT-LMM (Journal Club 09/04/2024)

  • Paper
  • Supplementary Information
  • Background Projections & LMM

REGENIE (Journal Club 11/04/2024)

  • Paper
  • Supplementary Information
  • LMM, Ridge Regression & PCA

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This work is licensed under the CC BY-NC-SA 4.0 licence.